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Science of fasting |
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Periodic fasting and CR prevent aging and rejuvenate the body |
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High-protein diet in middle age poses serious health risk |
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Treatment of Obesity through fasting |
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Management of Diabetes Through Intermittent Fasting |
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Longevity Gene: Another scientific step towards longer lives |
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Cholesterol Lowering Drug Statin Can Extend Lives of Cancer Patients |
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Fasting cycles retard growth of tumors |
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Intermittent Fasting for Prevention Obesity and Diabetes by |
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New compound in red wine (piceatannol) staves off obesity |
| Metabolic syndrome can be prevented and treated by fasting and caloric restriction. Clinical evidence: Effects of alternate fasting or very low calorie diet and low calorie diet on metabolic syndrome in severely obese patients. Tančić-Gajić M1, Vujović S, Vukčević M, Ivović M, Drezgić M, Marina L, Stojanović M, Arizanović Z, Nenezić A, Micić D. Hippokratia. 2012 Oct;16(4):335-41. BACKGROUND AND AIM: Weight loss improves the metabolic syndrome (MetS) features and related clinical abnormalities in obese subjects. The aim of this study was to assess the effects of a non-surgical therapeutic program on the MetS in severely obese patients. PATIENTS AND METHODS: Sixty-four extremely obese patients were involved in the therapeutic program, which consisted of two alternating phases: the three-week therapeutic fasting or semi-fasting in hospital conditions and the low calorie diet with dosed physical activity in outpatient conditions. At the baseline we measured: anthropometric parameters, blood pressure and lipid profile. Subjects underwent an oral glucose tolerance test and insulin resistance/sensitivity was evaluated by the homeostasis model assessment and the oral glucose insulin sensitivity. After weight reduction by at least 10%, all mentioned assessments were repeated. RESULTS: None of the patients had significant adverse effects. Forty-one patients aged 43.0±11.5 years completed the study. The mean weight loss was 27 kg or 18% of the initial weight (p<0.01), which was followed by a significant decrease of the insulin resistance, the overall prevalence of MetS (32%) and all MetS parameters, without the significant change in high-density lipoprotein. This weight loss pogram substantially improves the MetS in extremely obese patients. CONCLUSION: The tailored alternating either fasting or semi- fasting should be considered as an optional approach to manage extreme obesity and related metabolic abnormality. |
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